Probably the best thing about Island of Refuge is that I can't think of any book to compare it to. This shows originality, even though I found the storyline and characters to be a bit dull.
It's about several different people that are thrown together on a small island off of Maine. Strange things are happening there, including the untimely death of a young mother and her baby, and the frequent disappearances of a prominent figure.
The story doesn't even start to get interesting until near the middle. The characters introduced at the beginning don't have anything to with the point of the plot.
But these facts aren't really a problem because no one else has ever tried anything like that before. If the reader can stick with it, they're in for an original end. The ending is the best part. It's definitely worth your time.